I stated I would not have a red dot on a defensive handgun.This is just me, but I would shoot both eyes open like I always do and get my hits regardless. As long as the dot is visible you can make a shot easily. I believe Trijicon called it the Bindon Aiming Concept. Plus if your window is fogged up and you cannot use the Bindon concept how could you see the irons through the glass anyways?
Long guns have offset irons.