I am kind of partial to Smith and Wesson K 22 Master pieces/Model 17's
The Rugers are very popular, mainly due to their price and availability. But if you have a desire to shoot 10X bulls eyes then find a Smith & Wesson 41 or one of the classic High Standard pistols. The Supermatic Trophy, Citation, Victor along with the 41 have a trigger to die for. They are pricey and not in every gun shop.
A real sleeper is the discontinnued Smith & Wesson 422. I have owned one since they 1988. I have fed it thousands of every known 22 round made with no hic-ups, even when filthy. I can nail pop cans at 30 yards and man sized targets at 150 yards. ( I have witnesses)
If you are looking at Revolvers. There is only one choice. The Ruger Single Six. The balance and "point-ability" of this shooter can't be beat. I have taken running rabbits with mine. And with the magnum cylinder you have fire power that can take down coyotes or used in home defense.
I love shooting .22 handguns.
Do you prefer the Ruger Single Six even over the S&W Model 617?