The only downside to these pistols is that they are a bit tricky to take apart and put back together.
I have a total of 3 Ruger .22 semi auto pistols. 2 Mark II's and a Mark III. I have never found the need to disassemble them for any reason to clean them. It is totally unnecessary, and can often lead to frustration, and in some cases, damage to the gun itself. When they require a thorough cleaning I simply remove the magazine, lock the bolt open, and using a brush with a coffee can filled with clean Kerosene, or WD-40, (WD-40 smells better and is easier to obtain), I completely wet clean the entire pistol, flooding it liberally and using a short bristled paint brush to wash out any and all dirt and accumulated powder residue. You won't believe how much will come out. WD-40 and or Kerosene are avaliable from Home Depot and Lowe's in gallon size cans very reasonably, and neither one will harm wood grips or any plastic parts on the gun.
Once you have completely washed the weapon clean I then give it a blow dry with compressed air, being sure to blow out the bolt along with all of the nooks and crannies in the grip and magazine well. After that I give all moving surfaces a good oiling, and wipe the pistol down with oil as well. The gun will be as clean as if you disassembled it without all of the hassles and problems associated with taking these weapons apart. Especially when you consider the fact there is no advantage to doing it. Bill T.