My only advice-don't get a regular cab. There is a reason they don't make very many of them any more. Nobody wants them and they are hard to resell. I learned this lesson the hard way.
I would agree with this. Regular cab trucks are still around mainly as commercial vehicles.
I like my F250, the only thing besides the typical Ford rust I have dealt with is tires, oil, and now a master cylinder that went bad after someone rear ended me.