I can't speak to the PX4 but I've got over 700 rds. through my Nano and it is now my EDC. I like it for its simplicity, no safeties and good recoil for followup shots.
I wouldn't compare it to a Glock, though it has a "Glock-style" trigger. It's a little more blocky looking though it's very slim. It's DAO trigger which is around 6 pounds on mine.
The Nano and Glock triggers are nothing alike. Nano's trigger is a straight out DAO style, just like a revolver. Once you take up the slack on a Glock it's like a nice single action trigger. I own a Nano and a G26 and much prefer the Glock trigger.