If it is based off Lee's numbers, it will also be off one or two disks with almost every single powder.
And, your computer has a built-in calculator, also.
If you use the Lee Auto-Disk, you should keep track of the disk volume and the charge thrown. Take the charge weight and divide by the CC number and get the conversion factor. Multiply the next CC by the conversion factor and get a good estimate for the charge weight using your lot of powder. Keep records.
My disks/lot of powder gave me the following:
231/HP38 10.2 gn/cc
540/HS6 14.1 gn/cc
AA2 11.8 gn/cc
AA5 14.6 gn/cc
Clays 6.6 gn/cc
Herco 7.8 gn/cc
Power Pistol 11.1 gn/cc
Red Dot 6.4 gn/cc
Trail Boss 4.3 gn/cc
Unique 7.9 gn/cc
WAP/Silhouette 13.3 gn/cc
571/HS7 15.3 gn/cc
N310 9.2 gn/cc
WST 8.5 gn/cc