One 2003 Mazda MPV van on it's last leg at 197k (4 cat converters needing replaced soon, coolant leak in trans., **** poor design int he rear heater lines rusted out in rear wheel well) not worth fixing these.
One 2008 Mazda 3 @ 108k (just replaced clutch).
375,000 1994 Ford F250 IDI diesel (Banks turbo)
265,000 2000 Honda Insight, Lifetime mpg 54.7
2-3 or 450,000 miles 1966 mustang, restored multiple times, owned 25 years and it was old then!
I'd trust any of these long distance tonight, head to anywhere with no worries.