451_Detonics
Grandmaster
I would vote for the 22-250 for several reasons. It is a great round for accuracy, range, and is economic to shoot. I have been buying the BVAC 55 Grain V-max load for under $17 a box and it is excellent ammo...of course you can get bulk pack FMJ cheaper for practice. For example you can get PRVI for about 54 cents a round. In a Savage 12 series you are looking at a gun/ammo combo that will easily shoot 1/2 inch 100 yard groups.